Sunday, May 18, 2025
HomeNewsTechnologyHealth think tank Viruses can steal our genetic code to create new...

Health think tank Viruses can steal our genetic code to create new human-virus

Date:

Related stories

Barcelona Are Champions Again – Canaletas Erupts in Celebration

https://youtu.be/_I_gt6g3LYk FC Barcelona fans filled the streets in celebration Thursday...

Stadium Roars: PSL10 Hails Army Chief, Nation!

The Pakistan Super League (PSL10) match at Rawalpindi Cricket...

Why monkeys with smartphones showing in Rio de Janeiro?

https://youtu.be/QsxBkF2id9Q Monumental bronze sculptures of monkeys fixated on smartphones have...

PSL 10 Fights Back: War Can’t Stop Cricket!

The Pakistan Super League (PSL) Season 10 has roared...

Putin’s Zelensky Summit: Can It End the Ukraine War?

The Russia-Ukraine conflict, ongoing since Russia’s 2022 invasion, has...
spot_img

This finding is presented in a study published online today and in print June 25 in Cell.

The cross-disciplinary collaborative study was led by researchers at the Global Health and Emerging Pathogens Institute at Icahn School of Medicine at Mount Sinai in New York, and at the MRC-University of Glasgow Centre for Virus Research in the UK.

 

The cross-disciplinary team of virologists looked at a large group of viruses known as segmented negative-strand RNA viruses (sNSVs), which include widespread and serious pathogens of humans, domesticated animals and plants, including the influenza viruses and Lassa virus (the cause of Lassa fever).

They showed that, by stealing genetic signals from their hosts, viruses can produce a wealth of previously undetected proteins.

The researchers labeled them as UFO (Upstream Frankenstein Open reading frame) proteins, as they are encoded by stitching together the host and viral sequences. There was no knowledge of the existence of these kinds of proteins prior to this study.

 

These UFO proteins can alter the course of viral infection and could be exploited for vaccine purposes.

 

“The capacity of a pathogen to overcome host barriers and establish infection is based on the expression of pathogen-derived proteins,” said Ivan Marazzi, PhD, Associate Professor of Microbiology at Icahn School of Medicine and corresponding author on the study.

“To understand how a pathogen antagonizes the host and establishes infection, we need to have a clear understanding of what proteins a pathogen encodes, how they function, and the manner in which they contribute to virulence.”

 

Viruses cannot build their own proteins, so they need to feed suitable instructions to the machinery that builds proteins in their host’s cells.

Viruses are known to do this through a process called “cap-snatching,” in which they cut the end from one of the cell’s own protein-encoding messages (a messenger RNA, or mRNA) and then extend that sequence with a copy of one of their own genes. This gives a hybrid message to be read.

 

For more details 

NEWS DESK
NEWS DESKhttp://thinktank.pk
News Desk, where most of the News Item edit for THE THINK TANK JOURNAL editor@thinktank.pk

Latest stories

Publication:

spot_img

25 COMMENTS

  1. I’ve been surfing on-line more than 3 hours these days, yet
    I by no means discovered any interesting article like
    yours. It’s lovely value enough for me.

    Personally, if all web owners and bloggers made good content material as you probably did, the web might
    be much more useful than ever before.

  2. Ηello!
    Ρеrhaрѕ my mеssage is tоo spесifіс.
    Βut mу оlder sіster found а wondеrful mаn here аnd they have a greаt rеlationshір, but what аbоut me?
    Ι аm 23 yеаrs оld, Сhriѕtina, frоm thе Сzeсh Rеpubliс, knоw English languаgе аlѕо
    And… bеttеr tо ѕаy іt іmmedіatеly. Ι аm bіѕeхuаl. I аm nоt jеаlоus оf аnother womаn… esресiаlly іf wе make love togethеr.
    Ah yes, Ι сook very tаѕtу! and I lоve not оnly сoоk ;))
    Im real gіrl аnd lооking for ѕеrіouѕ and hоt relationѕhiр…
    Αnуway, you саn find mу prоfіlе here: http://giocantirousumtia.ga/usr-49868/

LEAVE A REPLY

Please enter your comment!
Please enter your name here

Privacy Overview

THE THINK TANK JOURNAL- ONLINE EDITION OF This website uses cookies so that we can provide you with the best user experience possible. Cookie information is stored in your browser and performs functions such as recognizing you when you return to our website and helping our team to understand which sections of the website you find most interesting and useful.