Recently, a team of investigators affiliated with the Francis I. Proctor Foundation at the University of California, San Francisco (UCSF), decided to investigate the potential of a common antibiotic — azithromycin — in treating mild-to-moderate cases of COVID-19 that do not require hospitalization.
The trial — called Azithromycin for COVID-19 Treatment, Investigating Outpatients Nationwide, or ACTION for short — will involve human participants, and the researchers started recruiting on May 26, 2020.
To learn more about the trial, and understand why the researchers chose to study azithromycin, despite specialists typically advising against antibiotics in the treatment of COVID-19
the trial’s principal investigators, Catherine Oldenburg, Sc.D, said that My team has been working with azithromycin and studying [it] for a number of indications for decades. Proctor [The Francis I. Proctor Foundation at UCSF], in general, has been working with azithromycin for trachoma control, which is an infection of the eye, [for] the last 20 years.
And so, in terms of trials [for] azithromycin, that’s something that we do a lot of. I have something like eight trials going on right now with azithromycin, most of which are for trachoma, or for childhood mortality in Sub-Saharan Africa